CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 57 enrolled
Drug / intervention
Bendamustine +6 moredrug
Likely dose
Bendamustine 30 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00916058
NCT00916058Phase 2Completed
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A Phase 1-2 Study of a Novel Conditioning Regimen of Bendamustine and Melphalan Followed by Autologous Stem Cell Transplant for Patients With Multiple Myeloma

Weill Medical College of Cornell University·interventional·Posted Jun 9, 2009·Updated Jun 4, 2019

In Brief

A Phase 2 clinical trial evaluating Bendamustine and Melphalan for Multiple Myeloma. Completed, enrolled 57 participants across 1 site.

Detailed Summary

The purpose of this study is to evaluate the safety and efficacy of Bendamustine (TREANDA™), in combination with Melphalan in subjects with multiple myeloma who are undergoing an Autologous Stem Cell Transplant.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsMultiple Myeloma
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
200920102011201220132014201520162017201820192020202120222023202420252026
First PostedJun 9, 2009
Enrollment StartApr 23, 2009
Primary CompletionMar 11, 2016
Study CompletionMar 1, 2018
TodayJul 2, 2026
Enrollment to primary: 6.9 yearsPosted 17.1 years ago

Interventions

Bendamustinedrug

30 mg/m\^2 given on day 2 of melphalan

Melphalandrug

100 mg/m\^2 for 2 days (70 mg/m\^2 for patients with Creatinine Clearance \<70 ml/min)

Bendamustinedrug

60 mg/m\^2 given on the 2nd day of melphalan

Bendamustinedrug

90 mg/m\^2 given on the 2nd day of melphalan

Bendamustinedrug

60 mg/m\^2 given on the 1st and 2nd day of melphalan

Bendamustinedrug

90 mg/m\^2 given on the 1st day of melphalan and 60 mg/m\^2 given on the 2nd day of melphalan

Bendamustinedrug

125 mg/m\^2 given on the 1st day of melphalan and 100mg/m\^2 given on the 2nd day of melphalan