CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 200 enrolled
Drug / intervention
Ibuprofen + Paracetamol +3 moredrug
Likely dose
Ibuprofen + Paracetamol 400 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00921700
NCT00921700Phase 4Completed
CompareCT.gov

Analgesic Effect of Ibuprofen 400 mg/Paracetamol 1000 mg, Ibuprofen 400 mg/ Paracetamol 1000 mg/60 mg Codeine, and Paracetamol 1000 mg/Codeine 60 mg: A Single-dose, Randomized, Placebo-controlled and Double-blind Study

Ullevaal University Hospital·interventional·Posted Jun 16, 2009·Updated Mar 30, 2016

In Brief

A Phase 4 clinical trial evaluating Ibuprofen + Paracetamol, Ibuprofen + Paracetamol + Codeine, and 2 other interventions for Pain, Postoperative. Completed, enrolled 200 participants across 1 site.

Detailed Summary

The purpose of this study is to determine whether the combination of paracetamol (acetaminophen) and other NSAIDs with or without weak opioids can give synergistic analgesic effect.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPain, Postoperative
CountriesNorway
CollaboratorsUniversity of Oslo

Timeline

Phase 4CompletedFinished
200920102011201220132014201520162017201820192020202120222023202420252026
First PostedJun 16, 2009
Enrollment StartJun 1, 2009
Primary CompletionNov 1, 2014
Study CompletionApr 1, 2015
TodayJul 2, 2026
Enrollment to primary: 5.4 yearsPosted 17.0 years ago

Interventions

Ibuprofen + Paracetamoldrug

Single oral dose of ibuprofen 400 mg combined with paracetamol (acetaminophen) 1000 mg in gelatine capsules

Ibuprofen + Paracetamol + Codeinedrug

Single oral dose of ibuprofen 400 mg combined with paracetamol (acetaminophen) 1000 mg and codeine 60 mg in gelatine capsules

Paracetamol + Codeinedrug

Single oral dose of paracetamol (acetaminophen) 1000 mg combined with codeine 60 mg in gelatine capsules

Placebodrug

Single oral dose of lactose as placebo in gelatine capsules