CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 10 enrolled
Drug / intervention
gabapentin +1 moredrug
Likely dose
gabapentin 1200 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00928954
NCT00928954N/ACompleted
CompareCT.gov

Investigation and Treatment of Ocular Motor Disorders: Cross-over Comparison of Gabapentin and Memantine as Treatment for Nystagmus

Case Western Reserve University·interventional·Posted Jun 26, 2009·Updated Jul 29, 2016

In Brief

A clinical study evaluating gabapentin and memantine for Nystagmus. Completed, enrolled 10 participants across 1 site.

Detailed Summary

Involuntary oscillations of the eyes (nystagmus) impairs vision so that affected patients, who have neurological disorders such as Multiple Sclerosis (MS) , cannot read or watch TV. Two medicines have been reported to suppress nystagmus and improve vision in such patients: gabapentin and memantine. The investigators set out to test which of these two drug was more effective by carrying out a double-blind cross-over study. In this way, we could determine which drug worked best in each patient.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsNystagmus
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedJun 26, 2009
Enrollment StartFeb 1, 2005
Primary CompletionMay 1, 2009
TodayJul 2, 2026
Enrollment to primary: 4.3 yearsPosted 17.0 years ago

Interventions

gabapentindrug

increasing to 1200 mg/day

memantinedrug

increasing to 40 mg/day