At a glance
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The Living Kidney Donor Safety Study (Long-term Effects of Becoming a Living Kidney Donor)
In Brief
An observational study for Living Kidney Donation. Completed, enrolled 1,438 participants across 13 sites in 2 countries.
Detailed Summary
The main goal of this study is to understand the long-term effects of kidney donation on blood pressure, kidney function, and patient-reported health-related quality of life. Living kidney donors and non-donor controls will be studied before and after the living donor transplant. The donors and non-donors will be followed for a minimum of 5 years and a maximum of 15 years. Both groups will be made up of healthy normotensive adults. The purpose of this study is to see if there are any long-term differences between the two groups regarding: 1. risk of hypertension 2. rate of kidney decline 3. risk of albuminuria 4. changes in health-related quality of life The study also looks to assess other outcomes, including: 1. understand and quantify the expenses incurred by donors 2. understand donor factors which influence recipient outcomes The pilot version of this study (The Long Term Medical and Psychological Implications of Becoming a Living Kidney Donor: A Prospective Pilot Study) began in 2004. Donors and controls in the pilot study were given the opportunity to continue on in the main study once it started in 2009.