CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 16 enrolled
Drug / intervention
Deep Brain Stimulationdevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00954421
NCT00954421N/ACompleted
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Use of Two DBS Electrodes to Treat Post-Traumatic Tremor

University of Florida·interventional·Posted Aug 7, 2009·Updated Jul 25, 2014

In Brief

A clinical study evaluating Deep Brain Stimulation for Multiple Sclerosis. Completed, enrolled 16 participants across 1 site.

Detailed Summary

The purpose of this research study is to: 1. Determine whether deep brain stimulation (DBS) with two leads (very thin coiled wires) placed unilaterally (on one side of the brain) is beneficial to patients with multiple sclerosis (MS) tremor. 2. Compare the two different locations of the DBS lead placement in effectiveness for treatment of muscle tremors that do not respond to treatment with medication caused by multiple sclerosis. 3. Evaluate any side effects that may result from the two DBS leads.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsMultiple Sclerosis
CountriesUnited States
CollaboratorsNational Institute of Neurological Disorders and Stroke (NINDS), Medtronic

Timeline

N/ACompletedFinished
200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedAug 7, 2009
Enrollment StartNov 1, 2006
Primary CompletionJun 1, 2012
Study CompletionDec 1, 2013
TodayJul 2, 2026
Enrollment to primary: 5.6 yearsPosted 16.9 years ago

Interventions

Deep Brain Stimulationdevice

Use of two ipsilateral thalamic Deep Brain Stimulation electrodes (one at the ventralis intermedius nucleus/ventralis oralis posterior nucleus border or VIM and one at the ventralis oralis anterior nucleus/ventralis oralis posterior nucleus border or VO) for treatment of disabling and medication refractory tremor secondary to head trauma or multiple sclerosis.