At a glance
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Topical Budesonide Treatment for Eosinophilic Esophagitis (EoE): Esophageal Medication Distribution, Treatment Response, and Effect on the Adrenal Axis.
In Brief
A clinical study evaluating inhaled/swallowed budesonide and viscous/swallowed budesonide for Eosinophilic Esophagitis. Completed, enrolled 25 participants across 1 site.
Detailed Summary
The purpose of this study is to conduct a clinical trial of two formulations of budesonide (nebulized/swallowed versus viscous/swallowed) in patients with EoE to determine if medication contact time and distribution in the esophagus relates to treatment response. The investigators will also determine if there is systemic absorption of these topical steroids. The investigators hypothesize that tissue and symptom response will correlate with esophageal medication contact time and distribution, and that significant systemic absorption will not be seen.
Study Details
Timeline
Interventions
medication will be nebulized and then swallowed
viscous suspension of budesonide will be swallowed