CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 28 enrolled
Drug / intervention
Angiotensin IIdrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00962949
NCT00962949Phase 1Completed
CompareCT.gov

The Renin-Aldosterone Axis in Postural Tachycardia Syndrome

Vanderbilt University Medical Center·interventional·Posted Aug 20, 2009·Updated Sep 16, 2025

In Brief

A Phase 1 clinical trial evaluating Angiotensin II for Postural Orthostatic Tachycardia Syndrome (POTS). Completed, enrolled 28 participants across 1 site.

Detailed Summary

The purpose of this study is to determine the role of the renin-angiotensin-aldosterone in the pathophysiology of postural tachycardia syndrome, and to provide an insight about the disease process in this disorder.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPostural Orthostatic Tachycardia Syndrome (POTS)
CountriesUnited States
Collaborators--

Timeline

Phase 1CompletedFinished
200920102011201220132014201520162017201820192020202120222023202420252026
First PostedAug 20, 2009
Enrollment StartApr 1, 2009
Primary CompletionDec 1, 2012
TodayJul 2, 2026
Enrollment to primary: 3.7 yearsPosted 16.9 years ago

Interventions

Angiotensin IIdrug

Angiotensin II infusion for 1 hour