At a glance
ClinicalIndex Comparison RecordN/ACompleted· 149 enrolled
Drug / intervention
metformin +1 moredrug
Likely dose
metformin 500 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Randomized Prospective Trial of Metformin Compared to Glyburide in Gestational Diabetes
In Brief
A clinical study evaluating metformin and Glyburide for Gestational Diabetes. Completed, enrolled 149 participants across 1 site.
Detailed Summary
Our hypothesis is that metformin and glyburide will have equal efficacy in controlling blood glucose in gestational diabetics with no increase in adverse maternal, fetal or neonatal outcomes.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsGestational Diabetes
CountriesUnited States
Collaborators--
Timeline
N/ACompletedFinished
2003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
Enrollment StartJul 2003
Primary CompletionMay 2008
First PostedAug 2009
Study CompletionAug 2023
TodayJul 2026
First PostedAug 26, 2009
Enrollment StartJul 1, 2003
Primary CompletionMay 1, 2008
Study CompletionAug 1, 2023
TodayJul 2, 2026
Enrollment to primary: 4.8 yearsPosted 16.8 years ago
Interventions
metformindrug
patients received glyburide initial dose of 500 mg PO BID. Increased as necessary to a maximum dose of 2000 mg QD to control blood glucose
Glyburidedrug
Initial dose of 2.5mg PO BID increased as necessary to a maximum dose of 20 mg (10mg BID) QD to control blood glucose