CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 223 enrolled
Drug / intervention
Unsupervised Decolonization +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00966446
NCT00966446N/ACompleted
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Epidemiology and Prevention of MRSA Transmission in the Community

University of Pennsylvania·interventional·Posted Aug 27, 2009·Updated Jul 5, 2019

In Brief

A clinical study evaluating Unsupervised Decolonization and Supervised Decolonization for MRSA - Methicillin Resistant Staphylococcus Aureus Infection. Completed, enrolled 223 participants across 4 sites.

Detailed Summary

The overall goal of this project is to elucidate the epidemiology of MRSA transmission in the community and test an intervention to prevent MRSA transmission in this setting.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsMRSA - Methicillin Resistant Staphylococcus Aureus Infection
CountriesUnited States
CollaboratorsPennsylvania Department of Health, Children's Hospital of Philadelphia, Milton S. Hershey Medical Center

Timeline

N/ACompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
First PostedAug 27, 2009
Enrollment StartSep 1, 2009
Primary CompletionSep 1, 2014
Study CompletionDec 1, 2014
TodayJul 2, 2026
Enrollment to primary: 5 yearsPosted 16.8 years ago

Interventions

Unsupervised Decolonizationdrug

Households will undergo decolonization for MRSA with Mupirocin nasal ointment and Hibiclens body wash. This means that the intervention includes applying Mupirocin ointment twice daily in each nostril for the first 7 days of study enrollment as well as using Hibliclens body wash twice total (on day 1 and day 7 of study enrollment) according to the instructions provided. Households are given detailed, written instructions and are asked to fill out logs tracking compliance for each household member.

Supervised Decolonizationdrug

Households will undergo decolonization for MRSA with Mupirocin nasal ointment and Hibiclens body wash. This means that the intervention includes applying Mupirocin ointment twice daily in each nostril for the first 7 days of study enrollment as well as using Hibliclens body wash twice total (on day 1 and day 7 of study enrollment) according to the instructions provided. Households are given detailed, written instructions and are asked to fill out logs tracking compliance for each household member. In addition, households are contacted by study stuff via phone or text messages to ensure compliance, to provide reminders to household members to perform the decolonization protocol as well as to answer any question/concerns household members may have.