CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 40 enrolled
Drug / intervention
Leucine +1 moredietary
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00968344
NCT00968344N/ACompleted
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An Integrated Low-Volume Nutritional Countermeasure to Maintain Muscle Mass and Function During Space Exploration

The University of Texas Medical Branch, Galveston·interventional·Posted Aug 31, 2009·Updated May 31, 2019

In Brief

A clinical study evaluating Leucine and Alanine for Muscle Loss. Completed, enrolled 40 participants across 1 site.

Detailed Summary

The investigators will test the following hypotheses: 1. Bedrest will blunt the anabolic response to a mixed nutrient meal, facilitating a loss of muscle mass and functional capacity that is only partially restored during rehabilitation. 2. Enriching daily meals with leucine will promote protein synthesis and maintain the anabolic response to mixed nutrient meal ingestion. This will preserve lean muscle mass and function during bedrest and facilitate the recovery of functional and metabolic capacity during rehabilitation.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsMuscle Loss
CountriesUnited States
CollaboratorsNational Space Biomedical Research Institute

Timeline

N/ACompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
First PostedAug 31, 2009
Enrollment StartAug 1, 2009
Primary CompletionApr 1, 2015
TodayJul 2, 2026
Enrollment to primary: 5.7 yearsPosted 16.8 years ago

Interventions

Leucinedietary

3-4g Leucine added to daily meals

Alaninedietary

Powered amino acid