CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 91 enrolled
Drug / intervention
Rapid-Acting Intramuscular Olanzapine +1 moredrug
Likely dose
Rapid-Acting Intramuscular Olanzapine 10 milligramfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00970281
NCT00970281Phase 3Completed

A Double-Blind Confirmatory Study Comparing Rapid-Acting Intramuscular Olanzapine and Rapid-Acting Intramuscular Placebo in Patients With an Exacerbation of Schizophrenia With Acute Psychotic Agitation

Eli Lilly and Company·interventional·Posted Sep 2, 2009·Updated Mar 7, 2012

In Brief

A Phase 3 clinical trial evaluating Rapid-Acting Intramuscular Olanzapine and Placebo for Schizophrenia. Completed, enrolled 91 participants across 11 sites.

Detailed Summary

The primary objectives of the study is to confirm if the efficacy of intramuscular injection (IM) olanzapine 10 milligrams (mg) in patients with an exacerbation of schizophrenia with acute psychotic agitation is greater than intramuscular placebo by comparing changes from baseline to 2 hours after the first IM injection of agitation.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsSchizophrenia
CountriesJapan
Collaborators--

Timeline

Phase 3CompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
First PostedSep 2, 2009
Enrollment StartSep 1, 2009
Primary CompletionApr 1, 2011
TodayJul 2, 2026
Enrollment to primary: 1.6 yearsPosted 16.8 years ago

Interventions

Rapid-Acting Intramuscular Olanzapinedrug

Administered by means of intramuscular injection (IM) with the possibility of second 10 milligram (mg) injection 2 to 4 hours after first injection, for a maximum of 2 injections

Placebodrug

Administered by means of IM with the possibility of second injection 2 to 4 hours after first injection, for a maximum of 2 injections