CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 120 target
Drug / intervention
Transversus abdominis plane (TAP) blockprocedure
Likely dose
Not stated in record
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Search/NCT00972920
NCT00972920N/ACompleted

Transversus Abdominis Plane (TAP) Block for Gynaecological Laparotomies - a Comparison of Ultrasound-guided Block and Blind Technique

Northern Health and Social Care Trust·interventional·Posted Sep 9, 2009·Updated Oct 21, 2015

In Brief

A clinical study evaluating Transversus abdominis plane (TAP) block for Laparotomy. Completed, enrolled 120 participants across 1 site.

Detailed Summary

Transversus abdominis plane (TAP) block is an application of local anaesthetic solution into the plane between internal oblique and transversus abdominis muscles at the triangle of Petit located superiorly to the iliac crests bilaterally. Anterior divisions of segmental spinal nerves, which provide innervation to the abdominal wall, run inside this compartment. TAP block been shown to provide good postoperative pain relief following surgical laparotomies, gynaecological laparotomies, appendicectomies, inguinal hernia repairs and open prostatectomies. The goal of this study is to compare the effect of blind and ultrasound-guided TAP block on postoperative pain relief and morphine consumption following to gynaecological laparotomies. Null research hypothesis for the study is that there is no difference between the performance (as defined by morphine consumption and patient satisfaction/ pain scores) of the TAP block procedure via 'blind' or ultrasound guided techniques for gynaecological laparotomies.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsLaparotomy
CountriesUnited Kingdom
Collaborators--

Timeline

N/ACompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
First PostedSep 9, 2009
Enrollment StartAug 1, 2009
Primary CompletionMay 1, 2012
Study CompletionJun 1, 2012
TodayJul 2, 2026
Enrollment to primary: 2.8 yearsPosted 16.8 years ago

Interventions

Transversus abdominis plane (TAP) blockprocedure

Application of local anaesthetic solution (LA) levo-bupivacaine (dose 1mg/kg for each side, concentration 2.5 mg/mL) between internal oblique abdominis muscle and transversus abdominis muscle on both sides.