At a glance
ClinicalIndex Comparison RecordPhase 2Completed· 50 enrolled
Drug / intervention
Premarin IV +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Resuscitative Endocrinology: (RESCUE - Shock): A Phase II Trial to Evaluate the Effects of Single Dose Intravenous Premarin for Treatment of Patients With Hemorrhagic Shock
University of Texas Southwestern Medical Center·interventional·Posted Sep 9, 2009·Updated Mar 19, 2020
In Brief
A Phase 2 clinical trial evaluating Premarin IV and Placebo for Hemorrhagic Shock. Completed, enrolled 50 participants across 2 sites.
Detailed Summary
Based on encouraging results from animal studies, the investigators hypothesize that early administration of IV Premarin® in patients with hemorrhagic shock will safely reduce secondary injury, and improve survival.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHemorrhagic Shock
CountriesUnited States
CollaboratorsUniversity of Washington, Resuscitation Outcomes Consortium
Timeline
Phase 2CompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
Enrollment StartJul 2009
First PostedSep 2009
Primary CompletionJan 2012
Study CompletionMay 2012
TodayJul 2026
First PostedSep 9, 2009
Enrollment StartJul 1, 2009
Primary CompletionJan 1, 2012
Study CompletionMay 1, 2012
TodayJul 2, 2026
Enrollment to primary: 2.5 yearsPosted 16.8 years ago
Interventions
Premarin IVdrug
One time dose of Premarin IV
Placebodrug
One time dose of placebo.