CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 83 enrolled
Drug / intervention
Proton Beam Irradiationradiation
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00976898
NCT00976898N/ACompleted

Phase II Study of Proton Beam Irradiation for the Treatment of Unresectable Hepatocellular Cancer and Cholangiocarcinoma

Massachusetts General Hospital·interventional·Posted Sep 15, 2009·Updated Sep 15, 2025

In Brief

A clinical study evaluating Proton Beam Irradiation for Liver Cancer. Completed, enrolled 83 participants across 4 sites.

Detailed Summary

In this study the investigators will be studying the effects of proton beam radiation therapy. This is a very accurate kind of treatment that has been shown to affect less normal tissue than a photon radiation beam. The accuracy allows the investigators to more safely increase the amount of radiation delivered to eliminate cancer. This accuracy will potentially reduce side effects that participants would normally experience using photon radiation therapy. The purpose of this study is to determine if radiation using proton beam therapy will kill the cancer cells in the participants liver.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsLiver Cancer
CountriesUnited States

Timeline

N/ACompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
First PostedSep 15, 2009
Enrollment StartAug 1, 2009
Primary CompletionMar 1, 2017
Study CompletionJul 1, 2018
TodayJul 2, 2026
Enrollment to primary: 7.6 yearsPosted 16.8 years ago

Interventions

Proton Beam Irradiationradiation

Given once a day, 5 days a week, for 3 weeks