CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 300 enrolled
Drug / intervention
TMP/SMX +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00976963
NCT00976963N/ACompleted
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Single Dose Monurol for Treatment of Acute Cystitis

University of Washington·interventional·Posted Sep 15, 2009·Updated Jun 5, 2023

In Brief

A clinical study evaluating TMP/SMX and Fosfomycin for Urinary Tract Infection. Completed, enrolled 300 participants across 1 site.

Detailed Summary

Urinary tract infecton (UTI) is a very common problem in young healthy women, afflicting approximately one-half of women by their late 20's. One of the most common antibiotics used to treat UTIs is Trimethoprim-Sulfamethoxazole (TMP-SMX), usually for total of three days. However, concerns about increased antibiotic resistance have led to increased interest in studying other antibiotics for UTI. An alternative antibiotic which is also FDA approved for the treatment of UTIs is fosfomycin (Monurol). The effectiveness of fosfomycin in curing UTIs when given as a single dose is not well studied. The purpose of this research study is to determine what the cure rates are with a single dose of fosfomycin versus the more standard 3-day course of TMP-SMX.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsUrinary Tract Infection
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
First PostedSep 15, 2009
Enrollment StartSep 17, 2009
Primary CompletionDec 27, 2016
TodayJul 2, 2026
Enrollment to primary: 7.3 yearsPosted 16.8 years ago

Interventions

TMP/SMXdrug

Take one twice daily for 3 days for urinary tract infection

Fosfomycindrug

Mix sachet with 1/2 glass cold water and stir. Drink immediately