CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 25,682 enrolled
Drug / intervention
Placebo & Aspirin +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00977938
NCT00977938Phase 4Completed

A Prospective, Multi-center, Randomized, Double-blind Trial to Assess the Effectiveness and Safety of 12 Versus 30 Months of Dual Antiplatelet Therapy in Subjects Undergoing Percutaneous Coronary Intervention With Either Drug-eluting Stent or Bare Metal Stent Placement for the Treatment of Coronary Artery Lesions

Baim Institute for Clinical Research·interventional·Posted Sep 16, 2009·Updated Jun 9, 2017

In Brief

A Phase 4 clinical trial evaluating Placebo & Aspirin and Clopidogrel & Aspirin, Prasugrel & Aspirin for Coronary Artery Disease. Completed, enrolled 25,682 participants across 256 sites in 10 countries.

Detailed Summary

The DAPT Study is a double blind randomized controlled trial intended to determine the appropriate duration for dual antiplatelet therapy (the combination of aspirin and a second anti-clotting medication) as well as the safety and effectiveness of dual antiplatelet therapy to protect patients from stent thrombosis and major adverse cardiovascular and cerebrovascular events (MACCE) following the implantation of drug-eluting coronary stents. Similar analysis will be conducted in a smaller cohort of bare metal coronary stent - treated subjects.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesAustralia, Czechia, France, Germany, Hungary, New Zealand, Poland, Romania, United Kingdom, United States

Timeline

Phase 4CompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
First PostedSep 16, 2009
Enrollment StartOct 1, 2009
Primary CompletionJun 1, 2014
TodayJul 2, 2026
Enrollment to primary: 4.7 yearsPosted 16.8 years ago

Interventions

Placebo & Aspirindrug

Clopidogrel & Aspirin, Prasugrel & Aspirindrug