At a glance
ClinicalIndex Comparison RecordPhase 2Completed· 34 enrolled
Drug / intervention
Broccoli sprout extract +1 moredrug
Likely dose
Mango juice 150 mLfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Evaluating the Effect of Broccoli Sprouts (Sulforaphane) on Cellular Proliferation, an Intermediate Marker of Breast Cancer Risk
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins·interventional·Posted Sep 23, 2009·Updated Nov 21, 2018
In Brief
A Phase 2 clinical trial evaluating Broccoli sprout extract and Mango juice for Breast Cancer. Completed, enrolled 34 participants across 1 site.
Detailed Summary
The purpose of this research is to examine the effect of a broccoli sprout preparation on specific factors in breast tissue that are related to breast cancer risk and to assess whether sulforaphane a key component of broccoli sprouts increases the levels of protective enzymes in breast tissue. In addition, the investigators will also examine how acceptable the broccoli sprouts preparation is to the study participants.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsBreast Cancer
CountriesUnited States
CollaboratorsBreast Cancer Research Foundation
Timeline
Phase 2CompletedFinished
200920102011201220132014201520162017201820192020202120222023202420252026
Enrollment StartApr 2009
First PostedSep 2009
Primary CompletionNov 2013
TodayJul 2026
First PostedSep 23, 2009
Enrollment StartApr 1, 2009
Primary CompletionNov 1, 2013
TodayJul 2, 2026
Enrollment to primary: 4.6 yearsPosted 16.8 years ago
Interventions
Broccoli sprout extractdrug
100 µmols of sulforaphane (dissolvable)
Mango juicedrug
150 mL of mango juice