CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 1,241 enrolled
Drug / intervention
V503 +4 morebiological
Likely dose
V503 0.5 mLfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00988884
NCT00988884Phase 3Completed

A Phase III Open-Label Clinical Trial to Study the Immunogenicity and Tolerability of V503 (A Multivalent Human Papillomavirus [HPV] L1 Virus-Like Particle [VLP] Vaccine) Given Concomitantly With Menactra™ and Adacel™ in Preadolescents and Adolescents (11 to 15 Year Olds)

Merck Sharp & Dohme LLC·interventional·Posted Oct 2, 2009·Updated Dec 14, 2018

In Brief

A Phase 3 clinical trial evaluating V503, Comparator: Menactra™ (Concomitant), and 3 other interventions for Human Papillomavirus Infection. Completed, enrolled 1,241 participants.

Detailed Summary

This study will evaluate the tolerability and immunogenicity of administration of the first dose of V503 at the same time as Menactra™ and Adacel™ versus administration of V503 one month prior to administration of Menactra™ and Adacel™.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
Countries--
Collaborators--

Timeline

Phase 3CompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
First PostedOct 2, 2009
Enrollment StartOct 21, 2009
Primary CompletionFeb 22, 2011
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 16.8 years ago

Interventions

V503biological

V503 (Multivalent HPV L1 VLP vaccine) given as a 0.5 mL intramuscular injection in the deltoid muscle of the non-dominant arm at Day 1, Month 2, and Month 6

Comparator: Menactra™ (Concomitant)biological

Menactra™ given as a single 0.5 mL intramuscular injection in the deltoid muscle of the dominant arm on Day 1.

Comparator: Adacel™ (Concomitant)biological

Adacel™ given as a single 0.5 mL intramuscular injection in the deltoid muscle of the dominant arm on Day 1.

Comparator: Menactra™ (Non-Concomitant)biological

Menactra™ given as a single 0.5 mL intramuscular injection in the deltoid muscle of the dominant arm at Month 1.

Comparator: Adacel™ (Non-concomitant)biological

Adacel™ given as a single 0.5 mL intramuscular injection in the deltoid muscle of the dominant arm at Month 1.