At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Pharmacological or Non-Pharmacological Management of Maternal Hypotension During Elective Cesarean Section Under Subarachnoid Anesthesia: a Randomized, Controlled Trial
In Brief
A Phase 4 clinical trial evaluating Bupivacaine, Morphine, and 4 other interventions for Pregnancy and 3 related conditions. Completed, enrolled 36 participants across 1 site.
Detailed Summary
The aim of this study is to compare two different therapeutic approaches to blood pressure reduction: pharmacological vs. non-pharmacological. The setting is that of patients undergoing scheduled Cesarean section under spinal anesthesia and suffering from aorta-caval compression syndrome, which causes a sudden drop in blood pressure.
Study Details
Timeline
Interventions
10 mg of a 5 mg/ml hyperbaric solution, intrathecally
200 µg of a 100 µg/ml solution, intrathecally
25 ml/min intravenously
37.5 mg/h intravenously
6.25 mg IV bolus prn. Hypotension defined according to study protocol for each arm.
0.1 mg/kg iv bolus prn Bradycardia defined as 50% drop in heart rate from baseline values.