CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 22 enrolled
Drug / intervention
Alfentanil +1 moredrug
Likely dose
Alfentanil 15 mcg/kgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00991809
NCT00991809N/ACompleted
CompareCT.gov

A Pilot Study of Prolonged, Intermittent Exposure to Alfentanil on Opioid-Induced Hyperalgesia in Healthy Volunteers

Johns Hopkins University·interventional·Posted Oct 8, 2009·Updated Oct 6, 2017

In Brief

A clinical study evaluating Alfentanil and Diphenhydramine for Hyperalgesia. Completed, enrolled 22 participants across 1 site.

Detailed Summary

The purpose of this study was to follow a person's response to experimental pain after multiple consecutive exposures to alfentanil or diphenhydramine to see if the person can tolerate the pain more, less, or the same at the end of the study.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHyperalgesia
CountriesUnited States
CollaboratorsNational Institute on Drug Abuse (NIDA)

Timeline

N/ACompletedFinished
200920102011201220132014201520162017201820192020202120222023202420252026
First PostedOct 8, 2009
Enrollment StartFeb 1, 2009
Primary CompletionMay 1, 2010
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 16.7 years ago

Interventions

Alfentanildrug

15 mcg/kg IM

Diphenhydraminedrug

25 mg IM