CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 107 enrolled
Drug / intervention
SABER-Bupivacaine Treatment 1a +5 moredrug
Likely dose
SABER-Bupivacaine Treatment 1a 5.0 mlfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00993798
NCT00993798Phase 2Completed

An International, Randomised, Double Blinded, Multi-centre, Active- and Placebo-controlled Dose Response Trial to Evaluate the Efficacy and Safety of SABER-Bupivacaine for Postoperative Pain Control in Patients Following Arthroscopic Shoulder Surgery

Durect·interventional·Posted Oct 12, 2009·Updated Jun 9, 2021

In Brief

A Phase 2 clinical trial evaluating SABER-Bupivacaine Treatment 1a, Placebo SABER-Bupivacaine Treatment 1b, and 4 other interventions for Postoperative Pain. Completed, enrolled 107 participants across 10 sites in 5 countries.

Detailed Summary

The objective is to identify the optimal dose of SABER-Bupivacaine for postoperative pain control in patients undergoing elective arthroscopic shoulder surgery on the basis of pharmacokinetics, efficacy and safety evaluations. The study duration consists of a screening period up to 14 days and a treatment period 14 days with a long term follow up visit at 6 months. The study will provide further data on safety.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesAustria, Germany, Latvia, Poland, Sweden
CollaboratorsNycomed

Timeline

Phase 2CompletedFinished
200920102011201220132014201520162017201820192020202120222023202420252026
First PostedOct 12, 2009
Enrollment StartApr 1, 2009
Primary CompletionJun 1, 2011
Study CompletionNov 1, 2011
TodayJul 2, 2026
Enrollment to primary: 2.2 yearsPosted 16.7 years ago

Interventions

SABER-Bupivacaine Treatment 1adrug

5.0 ml

Placebo SABER-Bupivacaine Treatment 1bdrug

5.0 ml

Bupivacaine HCl Treatment 1cdrug

20.0 ml

SABER-Bupivacaine Treatment 2adrug

7.5 ml

Placebo SABER-Bupivacaine Treatment 2bdrug

7.5 ml

Bupivacaine HCl Treatment 2cdrug

20.0 ml