At a glance
ClinicalIndex Comparison RecordPhase 4Completed· 20 enrolled
Drug / intervention
propofol +1 moredrug
Likely dose
propofol 1 mg/kgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Physiologic Stress During Procedural Sedation With and Without Alfentanil
In Brief
A Phase 4 clinical trial evaluating propofol and alfentanil for Sedation. Completed, enrolled 20 participants across 1 site.
Detailed Summary
This is a randomized clinical trial of deep procedural sedation with propofol with and without supplemental alfentanil. Patients will be assessed for total and fractionated serum catecholamines before and after the procedure in addition to usual procedural sedation outcomes parameters to assess the adrenergic effect of propofol sedation without supplemental opioid.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsSedation
CountriesUnited States
Collaborators--
Timeline
Phase 4CompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
Enrollment StartOct 2009
First PostedOct 2009
Primary CompletionOct 2012
Study CompletionDec 2012
TodayJul 2026
First PostedOct 19, 2009
Enrollment StartOct 1, 2009
Primary CompletionOct 1, 2012
Study CompletionDec 1, 2012
TodayJul 2, 2026
Enrollment to primary: 3 yearsPosted 16.7 years ago
Interventions
propofoldrug
1 mg/kg IV followed by 0.5 mg/kg iv prn sedation
alfentanildrug
alfentanil 10 ug/kg immediately prior to propofol dose