CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 96 enrolled
Drug / intervention
Estradiol +4 moredrug
Likely dose
Estradiol 1 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00997893
NCT00997893Phase 2Completed
CompareCT.gov

Effects of Estradiol and Soy on Menopausal Symptoms

University of Illinois at Chicago·interventional·Posted Oct 19, 2009·Updated Dec 7, 2020

In Brief

A Phase 2 clinical trial evaluating Soy Phytoestrogen, Estradiol, and 3 other interventions for Menopause and Hot Flashes. Completed, enrolled 96 participants across 1 site.

Detailed Summary

The purpose of this study is to determine the effects of oral estradiol and soy phytoestrogens on anxiety, stress responsivity and cognition in perimenopausal women.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsMenopause, Hot Flashes
CountriesUnited States
CollaboratorsNational Institute of Mental Health (NIMH)

Timeline

Phase 2CompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
First PostedOct 19, 2009
Enrollment StartDec 1, 2009
Primary CompletionMay 1, 2015
TodayJul 2, 2026
Enrollment to primary: 5.4 yearsPosted 16.7 years ago

Interventions

Soy Phytoestrogendietary

Novasoy® pill (55 mg)

Estradioldrug

Estradiol pill (1 mg)

Medroxyprogesterone Acetate (MPA)drug

medroxyprogesterone acetate (MPA) (10mg)

Soy Placebodrug

oral placebo pill (0mg Soy Phytoestrogen)

MPA Placebodrug

oral placebo pill (0mg MPA)