At a glance
ClinicalIndex Comparison RecordPhase 4Completed· 78 enrolled
Drug / intervention
Dexmedetomidine infusion +1 moredrug
Likely dose
propofol 1mg/kgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Comparison of Dexmedetomidine vs. Propofol in Vitreoretinal Surgery Under Sub-Tenon's Block
In Brief
A Phase 4 clinical trial evaluating Dexmedetomidine infusion and propofol for Retinal Detachment. Completed, enrolled 78 participants across 2 sites.
Detailed Summary
The investigators would like to determine if using Dexmedetomidine alone or in a reduced dose can prevent or reduce the incidence of adverse effects, while providing adequate sedation, and respiratory stability as compared to propofol.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsRetinal Detachment
CountriesUnited States
Collaborators--
Timeline
Phase 4CompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
Enrollment StartOct 2009
First PostedOct 2009
Primary CompletionMar 2013
Study CompletionNov 2013
TodayJul 2026
First PostedOct 26, 2009
Enrollment StartOct 1, 2009
Primary CompletionMar 1, 2013
Study CompletionNov 1, 2013
TodayJul 2, 2026
Enrollment to primary: 3.4 yearsPosted 16.7 years ago
Interventions
Dexmedetomidine infusiondrug
bolus of 0.5ug/kg intravenously over a period of 10-15 minutes, followed by an infusion of 0.2-0.7ug/kg/hr of drug
propofoldrug
propofol 1mg/kg intravenously as a bolus followed by 25-100ug/kg/min