CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 242 enrolled
Drug / intervention
L-methylfolate +2 moredrug
Likely dose
L-methylfolate 7.5 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01001559
NCT01001559N/ACompleted
CompareCT.gov

Combination Deplin® and Antidepressant Therapy Compared to Antidepressant Therapy Alone for an Episode of Major Depression- a Retrospective Analysis

Pamlab, Inc.·observational·Posted Oct 26, 2009·Updated Dec 19, 2013

In Brief

An observational study evaluating L-methylfolate, Selective serotonin reuptake inhibitor (SSRI), and 1 other intervention for Major Depressive Disorder. Completed, enrolled 242 participants across 1 site.

Detailed Summary

This is a retrospective chart review study to determine if Deplin® 7.5mg-15mg combined with an antidepressant is better than an antidepressant alone in adults with major depression.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsMajor Depressive Disorder
CountriesUnited States
CollaboratorsRed Oak Psychiatry Associates, PA, Baylor Health Care System

Timeline

N/ACompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
First PostedOct 26, 2009
Enrollment StartAug 1, 2009
Primary CompletionDec 1, 2010
Study CompletionJun 1, 2011
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 16.7 years ago

Interventions

L-methylfolatedrug

Subjects must have been on their respective therapies for a minimum of 60 days. L-methylfolate dosing was 7.5 mg or 15 mg daily

Selective serotonin reuptake inhibitor (SSRI)drug

Subject must have been on their respective therapy for a minimum of 60 days. Because this was an observational retrospective analysis, dosing of SSRI/SNRI varied on a per patient basis.

Serotonin and norepinephrine reuptake inhibitor (SNRI)drug

Subject must have been on their respective therapy for a minimum of 60 days. Because this was an observational retrospective analysis, dosing of SSRI/SNRI varied on a per patient basis.