At a glance
ClinicalIndex Comparison RecordPhase 4Completed· 123 enrolled
Drug / intervention
Metoclopramide +1 moredrug
Likely dose
Metoclopramide 20mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
An RCT of Metoclopramide/Diphenhydramine vs. Ketorolac Alone for Tension-type Headache
In Brief
A Phase 4 clinical trial evaluating Metoclopramide and Ketorolac for Headache. Completed, enrolled 123 participants across 1 site.
Detailed Summary
Occasionally, episodic tension-type headache may be severe enough to require an emergency department (ED) visit. The purpose of this study is to compare two commonly used medications to see which is better for tension type headache. Patients who present to the ED with an acute tension-type headache requiring treatment with injectable medication will be randomized to metoclopramide or ketorolac.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHeadache
CountriesUnited States
Collaborators--
Timeline
Phase 4CompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
Enrollment StartNov 2009
First PostedNov 2009
Primary CompletionSep 2012
Study CompletionNov 2012
TodayJul 2026
First PostedNov 11, 2009
Enrollment StartNov 1, 2009
Primary CompletionSep 1, 2012
Study CompletionNov 1, 2012
TodayJul 2, 2026
Enrollment to primary: 2.8 yearsPosted 16.6 years ago
Interventions
Metoclopramidedrug
metoclopramide 20mg IVSS + diphenhydramine 25mg IVSS
Ketorolacdrug
ketorolac 30mg IVSS