CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 20 enrolled
Drug / intervention
Bevacizumab, docetaxel, cisplatindrug
Likely dose
Bevacizumab, docetaxel, cisplatin 8 mg/kgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01025349
NCT01025349Phase 2Completed
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Retrospective Analysis of Salvage Therapy With Bevacizumab Plus Docetaxel and Cisplatin for Taiwanese Metastatic Breast Cancer

Taipei Medical University Hospital·interventional·Posted Dec 3, 2009·Updated Dec 3, 2009

In Brief

A Phase 2 clinical trial evaluating Bevacizumab, docetaxel, cisplatin for Metastatic Breast Cancer. Completed, enrolled 20 participants across 1 site.

Detailed Summary

Bevacizumab is a monoclonal antibody currently used for the treatment of colorectal cancer. It works by preventing the formation of new blood vessels (angiogenesis). The drug has been shown to inhibit vascular endothelial growth factor (VEGF) activity. Previous research showed positive findings in other solid tumors that had metastasized. In this study, the investigators are investigating the response of adding bevacizumab to conventional chemotherapy for metastatic breast cancer patients.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsMetastatic Breast Cancer
CountriesTaiwan
Collaborators--

Timeline

Phase 2CompletedFinished
20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedDec 3, 2009
Enrollment StartJan 1, 2005
Primary CompletionSep 1, 2009
TodayJul 2, 2026
Enrollment to primary: 4.7 yearsPosted 16.6 years ago

Interventions

Bevacizumab, docetaxel, cisplatindrug

Bevacizumab 8 mg/kg(over 60 minutes) on first day of first cycle, followed by 5 mg/kg on first day of the rest cycles, repeat every 2 weeks. docetaxel 45 mg/m2(over 60 minutes) on day 1 of each cycle, repeat every 2 weeks. cisplatin 50 mg/m2(over 4 hours) on day 1 of each cycle, repeat every 2 weeks.