CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 183 enrolled
Drug / intervention
amlodipine 5/10 mg per day plus valsartan 160 mg/day +1 moredrug
Likely dose
amlodipine 5/10 mg per day plus valsartan 160 mg/dayfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01030458
NCT01030458Phase 4Completed
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Newer vs Older Antihypertensive Agents in African Hypertensive Patients Trial

KU Leuven·interventional·Posted Dec 11, 2009·Updated Dec 9, 2013

In Brief

A Phase 4 clinical trial evaluating amlodipine 5/10 mg per day plus valsartan 160 mg/day and hydrochlorothiazide 6.25 mg/day plus bisoprolol 5/10 mg/day for Blood Pressure. Completed, enrolled 183 participants across 7 sites in 5 countries.

Detailed Summary

The purpose of this study is to compare the blood pressure lowering efficacy of a treatment regimen based on a dihydropyridine calcium-channel blocker combined with an angiotensin II type-1 receptor blocker with the recommended treatment regimen based on a low-dose thiazide diuretic combined with a beta-blocker.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsBlood Pressure
CountriesCameroon, Côte d’Ivoire, Gabon, Nigeria, Senegal
CollaboratorsUniversity of Kinshasa, Yaounde Central Hospital, University of Yaounde, University of Libreville, Institute of Cardiology Abidjan, University of Ilorin Teaching Hospital, University of Nigeria, Enugu Campus, Hospital Aristide Le Dantec, Dakar, Senegal

Timeline

Phase 4CompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
First PostedDec 11, 2009
Enrollment StartSep 1, 2010
Primary CompletionMar 1, 2012
TodayJul 2, 2026
Enrollment to primary: 1.5 yearsPosted 16.6 years ago

Interventions

amlodipine 5/10 mg per day plus valsartan 160 mg/daydrug

Amlodipine 5/10 mg/day plus valsartan 160 mg/day, once daily, in the morning

hydrochlorothiazide 6.25 mg/day plus bisoprolol 5/10 mg/daydrug

hydrochlorothiazide 6.25 mg/day plus bisoprolol 5/10 mg/day, once daily, in the morning