At a glance
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Confocal Laser Endomicroscopy for Assessment of Neoplasia After Mucosal Ablation or Resection of Gastrointestinal Neoplasia
In Brief
A clinical study evaluating Standard endoscopic evaluation and pCLE guided evaluation for Barrett Syndrome and 4 related conditions. Completed, enrolled 164 participants across 6 sites in 3 countries.
Detailed Summary
This study focuses on demonstrating the value of probe-based Confocal Laser Endomicroscopy (pCLE) in guiding endoscopic therapeutic procedures in Barrett's Esophagus (BE). It is a randomized controlled outcomes study including patients already treated for Barrett's Esophagus lesion(s) and undergoing high definition white light endoscopy follow up procedure, with or without pCLE (2 arms will be considered in this study). The procedures will be carried out per standards of practice with appropriately trained physicians.
Study Details
Timeline
Interventions
Treatment modalities can include endoscopic mucosal resection, radio-frequency ablation or photodynamic therapy
Treatment modalities include endoscopic mucosal resection, radio-frequency ablation, or photodynamic therapy. probe-based Confocal Laser Endomicroscopy is used to decide on re-treatment or not, and to guide and evaluate the treatment during the same endoscopic procedure.