CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 87 enrolled
Drug / intervention
Prednisone +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01042145
NCT01042145Phase 4Completed
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Community Care for Croup (RCT)

Washington University School of Medicine·interventional·Posted Jan 5, 2010·Updated Sep 15, 2014

In Brief

A Phase 4 clinical trial evaluating Prednisone and Dexamethasone for Croup. Completed, enrolled 87 participants across 1 site.

Detailed Summary

This randomized clinical trial was to compare the effectiveness of prednisone 2mg/kg/day for 3 days vs. dexamethasone 0.6mg/kg for 1 day for treatment of children with mild or moderate croup. It was conducted in a practice-based research network of community pediatricians in the St. Louis area. Outcomes included additional health care for croup, duration of symptoms, nights of disturbed sleep, parental stress, missed work days, and adverse events. Our hypothesis was that community-based treatment of children with mild or moderate croup with multiple doses of prednisone is superior to a single dose of dexamethasone.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCroup
CountriesUnited States
CollaboratorsWashington University Pediatric and Adolescent Ambulatory Research Consortium

Timeline

Phase 4CompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
First PostedJan 5, 2010
Enrollment StartOct 1, 2009
Primary CompletionJun 1, 2011
TodayJul 2, 2026
Enrollment to primary: 1.7 yearsPosted 16.5 years ago

Interventions

Prednisonedrug

2 mgs/kg for 3 days

Dexamethasonedrug

0.6 mgs for one day, then placebo for 2 days