At a glance
ClinicalIndex Comparison RecordN/ACompleted· 20 enrolled
Drug / intervention
Placebo +3 moredrug
Likely dose
Nebivolol 5 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Effect of Nebivolol on Blood Pressure in a Model of Hypertension Sensitive to Potentiation of Nitric Oxide Bioactivity
In Brief
A clinical study evaluating Placebo, Nebivolol 5 mg, and 2 other interventions for Hypertension and 2 related conditions. Completed, enrolled 20 participants across 1 site.
Detailed Summary
The purpose of this study is to evaluate the effect of the antihypertensive drug, nebivolol (Bystolic), compared to metoprolol (Lopressor) and sildenafil (Viagra) on blood pressure in patients with autonomic failure and supine hypertension.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
CollaboratorsForest Laboratories
Timeline
N/ACompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
Enrollment StartJan 2010
First PostedJan 2010
Primary CompletionJul 2014
Study CompletionAug 2014
TodayJul 2026
First PostedJan 8, 2010
Enrollment StartJan 1, 2010
Primary CompletionJul 1, 2014
Study CompletionAug 1, 2014
TodayJul 2, 2026
Enrollment to primary: 4.5 yearsPosted 16.5 years ago
Interventions
Placebodrug
Placebo capsule
Nebivolol 5 mgdrug
Nebivolol 5mg single oral dose
metoprolol tartrate 50 mgdrug
metoprolol tartrate 50 mg single oral dose
Sildenafil25 mgdrug
Sildenafil 25 mg single oral dose