CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 31 enrolled
Drug / intervention
Quinine +1 moredrug
Likely dose
Quinine 20 mg/kgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01047436
NCT01047436Phase 2Completed

An Open Label Randomised Comparative Trial to Establish the Efficacy of 3 mg/kg ArTiMist™ When Compared to Intravenous Quinine in Children With Severe or Complicated Falciparum Malaria, or Uncomplicated Falciparum Malaria With Gastrointestinal Complications

Proto Pharma Ltd·interventional·Posted Jan 12, 2010·Updated Jan 27, 2011

In Brief

A Phase 2 clinical trial evaluating Quinine and Artemether for Falciparum Malaria. Completed, enrolled 31 participants.

Detailed Summary

The purpose of this study is to compare the efficacy of Artemether Sublingual Spray (ArTiMist™) with intravenous quinine in children with severe or complicated falciparum malaria, or children with uncomplicated malaria with gastrointestinal complications.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
Countries--

Timeline

Phase 2CompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
First PostedJan 12, 2010
Enrollment StartDec 1, 2009
Primary CompletionJan 1, 2010
TodayJul 2, 2026
Enrollment to primary: 1 monthPosted 16.5 years ago

Interventions

Quininedrug

20 mg/kg intravenous quinine loading dose, followed by 10 mg/kg intravenously every 8 hours until resumption of normal oral therapy

Artemetherdrug

Artemether sublingual spray 3 mg/kg at protocol specified timepoints until resumption of normal oral therapy