At a glance
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The Effect of Systemic Prophylactic Dexamethasone on the Incidence of Postoperative Sore Throat in Patients Undergoing Ambulatory Laparoscopic Gynecologic Surgery: A Prospective, Randomized, Double Blinded, Placebo Controlled Trial
In Brief
A Phase 4 clinical trial evaluating Placebo administration, Dexamethasone 0.05mg/kr administration, and 1 other intervention for Sore Throat and Pain. Completed, enrolled 120 participants across 1 site.
Detailed Summary
Sore throat is a common postoperative complaint that can lead to morbidity and patient dissatisfaction . The incidence of sore throat has been reported to be between 6% and 90% even under optimal intubating conditions. There are several factors that have been shown to contribute to postoperative sore throat such as patient related factors, type of anesthesia and type of surgery. Corticosteroids are also commonly used in the perioperative period to potentiate analgesics and as antiemetics. The preoperative administration of dexamethasone can decrease the incidence and severity of postoperative sore throat which is rated by patients as one of the most undesirable outcomes in the postoperative period.
Study Details
Timeline
Interventions
Placebo administration
Dexamethasone 0.05mg/kr administered in 100ml of sterile saline solution prior to the start of surgery.
Dexamethasone 0.1mg/kg administered in 100ml of sterile saline solution prior to the beginning of surgery.