At a glance
ClinicalIndex Comparison RecordPhase 2Completed· 162 enrolled
Drug / intervention
Ferumoxytol +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Ferumoxytol Compared to Iron Sucrose Trial (FIRST): A Randomized, Multicenter, Trial of Ferumoxytol Compared to Iron Sucrose for the Treatment of Iron Deficiency Anemia in Adult Subjects With Chronic Kidney Disease
In Brief
A Phase 2 clinical trial evaluating Ferumoxytol and Iron Sucrose for Iron Deficiency and 2 related conditions. Completed, enrolled 162 participants across 36 sites in 7 countries.
Detailed Summary
The purpose of the study is to evaluate the safety and efficacy of intravenous (IV) ferumoxytol compared to IV iron sucrose for the treatment of iron deficiency anemia (IDA) in participants with chronic kidney disease (CKD).
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsIron Deficiency, Anemia, Kidney Disease
CountriesBelgium, Canada, Germany, India, Poland, United Kingdom, United States
Collaborators--
Timeline
Phase 2CompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
First PostedJan 2010
Enrollment StartMar 2010
Primary CompletionJul 2011
Study CompletionApr 2012
TodayJul 2026
First PostedJan 20, 2010
Enrollment StartMar 1, 2010
Primary CompletionJul 19, 2011
Study CompletionApr 19, 2012
TodayJul 2, 2026
Enrollment to primary: 1.4 yearsPosted 16.4 years ago
Interventions
Ferumoxytoldrug
IV Ferumoxytol
Iron Sucrosedrug
IV Iron Sucrose