At a glance
ClinicalIndex Comparison RecordPhase 2Completed· 80 enrolled
Drug / intervention
Oxaliplatin +4 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Phase II Evaluation of Five Fractions of Radiotherapy Followed by Full Dose FOLFOX Chemotherapy as Preoperative Treatment for Rectal Cancer
In Brief
A Phase 2 clinical trial evaluating External beam radiation, Oxaliplatin, and 3 other interventions for Rectal Neoplasms. Completed, enrolled 80 participants across 1 site.
Detailed Summary
To determine if short course radiotherapy followed by chemotherapy can maintain morbidity at or below levels reported with concurrent 5FU, oxaliplatin, and radiotherapy, while maintaining response rates comparable to what would be expected with radiotherapy and concurrent chemotherapy.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsRectal Neoplasms
CountriesUnited States
Collaborators--
Timeline
Phase 2CompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
Enrollment StartNov 2009
First PostedFeb 2010
Primary CompletionApr 2013
Study CompletionSep 2014
TodayJul 2026
First PostedFeb 1, 2010
Enrollment StartNov 1, 2009
Primary CompletionApr 1, 2013
Study CompletionSep 1, 2014
TodayJul 2, 2026
Enrollment to primary: 3.4 yearsPosted 16.4 years ago
Interventions
External beam radiationradiation
Oxaliplatindrug
Leucovorindrug
5-FUdrug
Capecitabinedrug