At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
The LIFE Study - Lifestyle Interventions and Independence for Elders
In Brief
A Phase 3 clinical trial evaluating Physical Activity and Successful Aging for Sedentary Lifestyle and 2 related conditions. Completed, enrolled 1,635 participants across 8 sites.
Detailed Summary
Based upon promising results from a pilot study among 424 sedentary older adults who were randomized to a physical activity intervention or a successful aging health education intervention, a Phase 3 multi-center randomized controlled trial is being conducted to compare a moderate-intensity physical activity program to a successful aging health education program in 1,600 sedentary older adults who are followed for an average of 2.7 years. The primary aim was to assess the long-term effects of the proposed interventions on the primary outcome of major mobility disability, defined as inability to walk 400 m.
Study Details
Timeline
Interventions
The physical activity intervention consists primarily of walking at moderate intensity, lower extremity resistance exercises, balance exercises, stretching and behavioral counseling.
The successful aging intervention consists of health education seminars regarding health-related matters and upper extremity stretching exercises.