CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 298 enrolled
Drug / intervention
olaparibdrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01078662
NCT01078662Phase 2Completed

A Phase II, Open Label, Non Randomised, Non Comparative, Multicentre Study to Assess the Efficacy and Safety of Olaparib Given Orally Twice Daily in Patients With Advanced Cancers Who Have a Confirmed Genetic BRCA 1 and/or BRCA2 Mutation

AstraZeneca·interventional·Posted Mar 2, 2010·Updated Aug 13, 2025

In Brief

A Phase 2 clinical trial evaluating olaparib for Ovarian and 4 related conditions. Completed, enrolled 298 participants across 14 sites in 6 countries.

Detailed Summary

To assess the efficacy of oral olaparib in patients with advanced cancer who have a confirmed genetic BRCA1 and/or BRCA2 mutation, by assessment of tumour response

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesAustralia, Germany, Israel, Spain, Sweden, United States
Collaborators--

Timeline

Phase 2CompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
First PostedMar 2, 2010
Enrollment StartFeb 21, 2010
Primary CompletionJul 31, 2012
Study CompletionAug 12, 2024
TodayJul 2, 2026
Enrollment to primary: 2.4 yearsPosted 16.3 years ago

Interventions

olaparibdrug

Tablets Oral BID