At a glance
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An Acupuncture fMRI Study on Chronic Pain: Response Reliability and Dose Effect
In Brief
A clinical study evaluating acupuncture for Osteoarthritis, Knee. Completed, enrolled 44 participants across 1 site.
Detailed Summary
In this proposal, we plan to dynamically investigate brain response to verum acupuncture (of two different "doses") and placebo acupuncture, using a paradigm that approximates clinical acupuncture practice across multiple treatment sessions in knee osteoarthritis (OA) patients. This proposal aims to: 1) characterize session-to-session brain responses to verum / sham acupuncture treatment (reliability of response) for OA patients, and 2) investigate how different "doses" of acupuncture influence brain response and acupuncture efficacy (impact of dose). The findings of this project will deepen our biological understanding on why and how acupuncture can treat chronic pain and what happens in the brain during the multiple-session acupuncture treatment.
Study Details
Timeline
Interventions
patient will receive high dose, low dose or sham acupuncture treatment.