CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 134 enrolled
Drug / intervention
RENEWbehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01080196
NCT01080196N/ACompleted
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Reducing Falls With RENEW in Older Adults Who Have Fallen

University of Utah·interventional·Posted Mar 3, 2010·Updated Jun 21, 2022

In Brief

A clinical study evaluating RENEW for Muscle Atrophy and Physical Deconditioning. Completed, enrolled 134 participants across 1 site.

Detailed Summary

This clinical trial will compare the effects of a high intensity Resistance Exercise via Negative Work (RENEW) vs. Traditional resistance exercise (TRAD) as part of a mult-component exercise and fall-reduction program on muscle conditioning; falling risks; as well as the fall incidence in older adults who have fallen. We anticipate that muscle conditioning will mediate the effect of RENEW on falling risks and fall incidence.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsMuscle Atrophy, Physical Deconditioning
CountriesUnited States
CollaboratorsDepartment of Health and Human Services, National Institutes of Health (NIH), National Institute on Aging (NIA)

Timeline

N/ACompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedMar 3, 2010
Enrollment StartApr 1, 2008
Primary CompletionFeb 1, 2014
TodayJul 2, 2026
Enrollment to primary: 5.8 yearsPosted 16.3 years ago

Interventions

RENEWbehavioral

RENEW will occur on a recumbent ergometer that appears like a normal stepper ergometer. While resisting the foot pedal movement the participant experiences eccentric muscle contractions about the knee and hip while performing negative work. The progression of the 3 x/week (every other day), 12 week RENEW program will be determined as a function of the rating of perceived exertion (RPE) using a "target" workload on the monitor. RENEW will be increased very slowly over the first 3 weeks and, subsequently, to maintain an 11-13 perceived exertion. During the formal RENEW training regimen the participants become fully acclimated to the device (week 3-4) the total RENEW load will increase weekly with no increase in their RPE.