CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 96 enrolled
Drug / intervention
phenylephrine +2 moredrug
Likely dose
phenylephrine 100 mcgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01080625
NCT01080625N/ACompleted
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Effect of Preventive Medicine on the Postreperfusion Syndrome

Seoul National University Hospital·interventional·Posted Mar 4, 2010·Updated May 3, 2012

In Brief

A clinical study evaluating phenylephrine, epinephrine, and 1 other intervention for Hypotension After Reperfusion in Liver Transplantation. Completed, enrolled 96 participants across 1 site.

Detailed Summary

Postreperfusion syndrome (PRS) is a relatively common phenomenon in patients undergoing liver transplantation which is characterized by an acute drop in blood pressure immediately after the prefusion is restored to the transplanted liver. We hypothesized that PRS would be prevented when phenylephrine or epinephrine is administered immediately prior to reperfusion in liver transplantation.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHypotension After Reperfusion in Liver Transplantation
CountriesSouth Korea
Collaborators--

Timeline

N/ACompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
First PostedMar 4, 2010
Enrollment StartApr 1, 2010
Primary CompletionSep 1, 2011
Study CompletionOct 1, 2011
TodayJul 2, 2026
Enrollment to primary: 1.4 yearsPosted 16.3 years ago

Interventions

phenylephrinedrug

100 mcg of phenylephrine (volume 10 ml) iv at the time of reperfusion

epinephrinedrug

10mcg of epinephrine (volume 10 ml) is administered iv at the time of reperfusion

placebo controldrug

10ml of normal saline is administered at the time of reperfusion