At a glance
ClinicalIndex Comparison RecordPhase 2Completed· 60 enrolled
Drug / intervention
caffeine/propranolol combination tablet +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Randomized Double-Blind Study to Evaluate the Dose-Related Efficacy and Safety of Caffeine/Propranolol in the Treatment of Acute Migraine
In Brief
A Phase 2 clinical trial evaluating caffeine/propranolol combination tablet and placebo for Migraine Disorders. Completed, enrolled 60 participants across 1 site.
Detailed Summary
This is a research study to assess the safety of caffeine/propranolol at different dose levels. We want to find out what effects, good and/or bad, it has on patients and their migraines.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsMigraine Disorders
CountriesUnited States
Collaborators--
Timeline
Phase 2CompletedFinished
200720082009201020112012201320142015201620172018201920202021202220232024202520262027
Enrollment StartJan 2007
Primary CompletionSep 2009
Study CompletionDec 2009
First PostedMar 2010
TodayJul 2026
First PostedMar 4, 2010
Enrollment StartJan 1, 2007
Primary CompletionSep 1, 2009
Study CompletionDec 1, 2009
TodayJul 2, 2026
Enrollment to primary: 2.7 yearsPosted 16.3 years ago
Interventions
caffeine/propranolol combination tabletdrug
caffeine/propranolol combination tablet administered orally once daily
placebodrug
placebo to match caffeine/propranolol combination tablet administered orally once daily