CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 314 enrolled
Drug / intervention
Extended-release Guanfacine Hydrochloride +1 moredrug
Likely dose
Extended-release Guanfacine Hydrochloride 4mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01081132
NCT01081132Phase 3Completed

A Phase 3, Double-blind, Randomized, Multi-center, Placebo Controlled, Dose-optimization Study Evaluating the Safety, Efficacy, and Tolerability of Once Daily Dosing With Extended-release Guanfacine Hydrochloride in Adolescents Aged 13-17 Years Diagnosed With Attention-deficit/Hyperactivity Disorder (ADHD)

Shire·interventional·Posted Mar 5, 2010·Updated Jun 28, 2021

In Brief

A Phase 3 clinical trial evaluating Extended-release Guanfacine Hydrochloride and Placebo for Attention-Deficit/Hyperactivity Disorder. Completed, enrolled 314 participants across 54 sites.

Detailed Summary

To assess the efficacy of optimized Extended-release Guanfacine Hydrochloride compared with placebo in the treatment of adolescents aged 13-17 years with a diagnosis of ADHD as measured by the ADHD-RS-IV

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 3CompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
First PostedMar 5, 2010
Enrollment StartSep 19, 2011
Primary CompletionMay 16, 2013
TodayJul 2, 2026
Enrollment to primary: 1.7 yearsPosted 16.3 years ago

Interventions

Extended-release Guanfacine Hydrochloridedrug

The test product will be provided as 1, 2, 3, and 4mg tablets. Subjects will be administered a once-daily dose between 1-7mg/day depending on weight.

Placeboother

Matching placebo will be provided as 1,2,3, and 4mg tablets. Subjects will be administered a once-daily dose of placebo between 1-7mg/day depending on weight.