CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 332 enrolled
Drug / intervention
Placebo +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01081678
NCT01081678Phase 2Completed

A Multi-center, Randomized, Double-blind, Placebo-controlled Study to Determine the Efficacy, Safety, and Tolerability of AMG 785 in Adults With a Fresh Unilateral Hip Fracture, Status Post Surgical Fixation

Amgen·interventional·Posted Mar 5, 2010·Updated Sep 21, 2022

In Brief

A Phase 2 clinical trial evaluating Placebo and Romosozumab for Fracture Healing. Completed, enrolled 332 participants across 99 sites in 24 countries.

Detailed Summary

This is an international, multi-center study to determine the efficacy, safety, and tolerability of romosozumab (AMG 785) in adults with a fresh unilateral hip fracture, status post surgical fixation.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesArgentina, Australia, Belgium, Bulgaria, Canada, Denmark, Estonia, Finland, Germany, Greece, Hong Kong, Hungary, India, Italy, Latvia, Lithuania, Netherlands, New Zealand, Poland, Slovenia, Sweden, Switzerland, United Kingdom, United States
Collaborators--

Timeline

Phase 2CompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
First PostedMar 5, 2010
Enrollment StartJun 20, 2010
Primary CompletionJun 30, 2012
Study CompletionMay 10, 2013
TodayJul 2, 2026
Enrollment to primary: 2.0 yearsPosted 16.3 years ago

Interventions

Placebodrug

Administered by subcutaneous (under the skin) injection

Romosozumabdrug

Administered by subcutaneous injection