CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 1,000 enrolled
Drug / intervention
Cardiac Computed Tomographyradiation
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01084239
NCT01084239Phase 3Completed
CompareCT.gov

Rule Out Myocardial Ischemia/Infarction by Computer Assisted Tomography

Massachusetts General Hospital·interventional·Posted Mar 10, 2010·Updated May 7, 2014

In Brief

A Phase 3 clinical trial evaluating Cardiac Computed Tomography for Acute Coronary Syndrome and 2 related conditions. Completed, enrolled 1,000 participants across 1 site.

Detailed Summary

The growing availability of cardiac computed tomography (CT)\* in emergency departments (EDs) across the U.S. expands the opportunities for its clinical application, but also heightens the need to define its appropriate use in the evaluation of patients with acute chest pain. To address this need, we performed a randomized diagnostic trial (RDT) to determine whether integrating cardiac CT, along with the information it provides on coronary artery disease (CAD) and left ventricular (LV) function, can improve the efficiency of the management of these patients (i.e. shorten length of hospital stay, increase direct discharge rates from the ED, decreasing healthcare costs and improving cost effectiveness while being safe).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAcute Coronary Syndrome, Myocardial Infarction, Unstable Angina Pectoris
CountriesUnited States
CollaboratorsNational Heart, Lung, and Blood Institute (NHLBI), Kaiser Permanente, Beth Israel Deaconess Medical Center, Bay State Clinical Trials, Inc., Washington University School of Medicine, Tufts Medical Center, The Cleveland Clinic, Northwestern University, University of Maryland

Timeline

Phase 3CompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
First PostedMar 10, 2010
Enrollment StartApr 1, 2010
Primary CompletionJan 1, 2012
Study CompletionMar 1, 2012
TodayJul 2, 2026
Enrollment to primary: 1.8 yearsPosted 16.3 years ago

Interventions

Cardiac Computed Tomographyradiation

A contrast enhanced cardiac CT was performed in addition to standard evaluation. Reconstructed data sets were evaluated for the presence of coronary artery calcium, coronary atherosclerotic plaque and stenosis, LV function and incidental findings.