At a glance
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Local Anesthetic Use at Iliac Crest Bone Graft Site in Spinal Reconstructive Surgery
In Brief
A clinical study evaluating Bupivacaine and Normal Saline for Pain. Completed, enrolled 40 participants across 1 site.
Detailed Summary
The use of iliac crest bone graft (ICBG) remains the gold-standard in spinal reconstructive surgery for achieving fusion. Major complications from the harvesting of ICBG are rare, but chronic pain has been reported in 10-39%. Catheters implanted at the time of surgery have been used to provide local anesthetic at the harvest site for 24-48 hours after surgery. This has been shown to decrease chronic pain at 4 years post-operatively. A single application of local anesthetic at surgery has been shown to decrease pain at the harvest site for up to 5 days. No study has demonstrated a benefit to using a single application of local anesthetic at the ICBG site beyond 5 days. In current clinical practice, the use of a local anesthetic at the ICBG site is determined according to surgeon preference. The purpose of this study is to determine if a single application of bupivacaine at the ICBG site, as currently done in some cases, provides any pain relief beyond 5 days such as that demonstrated with longer infusions of local anesthetics.
Study Details
Timeline
Interventions
Single application of 10ml of bupivacaine 0.5% into the iliac crest bone harvest surgical site.
Normal saline 0.9%, 10ml, single application directly into iliac crest bone harvest surgical site.