CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 161 enrolled
Drug / intervention
SPD489 +1 moredrug
Likely dose
SPD489 70 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01101022
NCT01101022Phase 4Completed

A Phase 4, Randomized, Double-Blind, Multicenter, Placebo-controlled, Parallel Group Study Evaluating the Safety and Efficacy of SPD489 on Executive Function (Self-Regulation) Behaviors in Adults With Attention-Deficit/Hyperactivity Disorder (ADHD) Reporting Clinically Significant Impairment of Real-World Executive Function Behavior.

Shire·interventional·Posted Apr 9, 2010·Updated Jun 9, 2021

In Brief

A Phase 4 clinical trial evaluating SPD489 and Placebo for ADHD Specifically With Executive Function Impairment. Completed, enrolled 161 participants across 39 sites.

Detailed Summary

The primary objective of the study is to evaluate the efficacy of SPD489 compared to placebo on executive function (self-regulation) behaviors in adults with ADHD who report clinically significant impairment of executive function behavior in their everyday environment, as measured by the self-report Behavior Rating Inventory of Executive Function - Adult Version (BRIEF-A) Global Executive Composite (GEC) T-score.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
First PostedApr 9, 2010
Enrollment StartMay 19, 2010
Primary CompletionNov 29, 2010
TodayJul 2, 2026
Enrollment to primary: 6 monthsPosted 16.2 years ago

Interventions

SPD489drug

1 capsule per day (30, 50 or 70 mg), daily throughout the double-blind treatment period (10 weeks)

Placeboother

1 capsule per day, daily throughout the double-blind treatment period (10 weeks)