At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Pioglitazone as an Adjunct for Moderate to Severe Depressive Disorder
In Brief
A Phase 3 clinical trial evaluating Pioglitazone+Citalopram+Chlordiazepoxide and Placebo+ Citalopram+ Chlordiazepoxide for Major Depressive Disorder. Completed, enrolled 50 participants across 1 site.
Detailed Summary
The purpose of this study is to determine whether Pioglitazone as an adjunct to Citalopram is effective in treatment of moderate to severe depression
Study Details
Timeline
Interventions
Pioglitazone 15 mg every 12 hours for six weeks Citalopram 20 mg per day for week one, and then 30 mg/day for 5 consecutive weeks. Chlordiazepoxide 10 mg each night for first three weeks
Placebo 1 Q12h for 6 weeks with the same shape and color as Pioglitazone. Citalopram 20 mg per day for week one, and then 30 mg/day for 5 consecutive weeks. Chlordiazepoxide 10 mg each night for first three weeks