CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 150 enrolled
Drug / intervention
prophylaxis +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01115153
NCT01115153N/ACompleted
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Prophylaxis With Single Versus Five Dose of Antibiotic Therapy as Treatment of Patients With Gangrenous Acute Appendicitis (Randomized, Controlled Clinical Trial)

Universidad Industrial de Santander·interventional·Posted May 4, 2010·Updated Aug 23, 2011

In Brief

A clinical study evaluating prophylaxis and therapy for Gangrenous Appendicitis. Completed, enrolled 150 participants across 1 site.

Detailed Summary

A prospective, randomized controlled clinical trial was conducted at the Hospital Universitario de Santander to test the effectiveness of providing a single 1-dose therapy of antibiotic prophylaxis versus a 5-day antibiotic therapy in patients with acute gangrenous appendicitis.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsGangrenous Appendicitis
CountriesColombia
CollaboratorsHospital Universitario de Santander

Timeline

N/ACompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedMay 4, 2010
Enrollment StartDec 1, 2007
Primary CompletionNov 1, 2009
Study CompletionFeb 1, 2010
TodayJul 2, 2026
Enrollment to primary: 1.9 yearsPosted 16.2 years ago

Interventions

prophylaxisother

single doses of antibiotics before surgery in patients with gangrenous appendicitis Metronidazole 500 mg IV + amikacin 1 gr IV

therapyother

antibiotic treatment (5 days) therapy in patients with gangrenous appendicitis metronidazole 500 mg IV three times a day + amikacin 1 gr IV per day