CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 270 enrolled
Drug / intervention
Community Reinforcement Approach (CRA) + HIV prevention +2 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT01143792
NCT01143792Phase 2Completed

Evaluation of Treatments for Homeless Youth: CRA, MET and Case Management

Ohio State University·interventional·Posted Jun 14, 2010·Updated Apr 16, 2013

In Brief

A Phase 2 clinical trial evaluating Community Reinforcement Approach (CRA) + HIV prevention, Case Management + HIV Prevention, and 1 other intervention for Substance Abuse. Completed, enrolled 270 participants across 1 site.

Detailed Summary

Youth who leave home for the streets are at significantly more risk for a multitude of problems, yet little research is available to guide treatment intervention efforts with this population. Studies document high rates of substance use, HIV risk, mental health problems, teenage pregnancy and criminality. Research to date examining homeless, street living youth has been primarily descriptive; less effort has been directed towards developing and evaluating treatment interventions for this group. The majority of homeless youth do not receive substance abuse treatment, with one study reporting that only 15% of street living youth report ever receiving mental health services. The effectiveness of the Community Reinforcement Approach (CRA) with street living youth was studied in our recently completed Stage 1 trial. The proposed study is a Stage II clinical trial examining outcome of CRA individual therapy as compared to two interventions commonly employed, yet little researched, with this group. All clients will be randomized to one of three theoretically distinct interventions: (1) CRA therapy, (2) Motivational Enhancement Therapy (MET), or (3) Case Management (CM). The relative effectiveness of these interventions will be evaluated at 3, 6, and 12 months post-baseline. The Social Ecology Theory of Development (Bronfenbrenner, 1979) guides our change hypotheses and intervention. Proposed change mechanisms (mediators) for each intervention will be evaluated. Differential treatment response as a function of ethnicity, gender, age, sexual orientation and abuse (moderators) will be investigated to better understand the interventions. The study will also examine how, if at all, treatment engagement, retention and expectations impact youth response to the three treatments. Information gained through this project may help address the gap in our understanding of how best to effectively intervene with a group at high risk for continuing health and psychological problems.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsSubstance Abuse
CountriesUnited States

Timeline

Phase 2CompletedFinished
200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedJun 14, 2010
Enrollment StartSep 1, 2006
Primary CompletionDec 1, 2010
Study CompletionJun 1, 2012
TodayJul 2, 2026
Enrollment to primary: 4.3 yearsPosted 16.1 years ago

Interventions

Community Reinforcement Approach (CRA) + HIV preventionbehavioral

12 sessions of the CRA and 2 sessions of HIV prevention.

Case Management + HIV Preventionbehavioral

12 sessions of case management and 2 sessions of HIV prevention.

Motivational Enhancement Therapy (MET) + HIV preventionbehavioral

2 sessions of MET and 2 sessions of HIV prevention.