At a glance
ClinicalIndex Comparison RecordEarly Ph 1Completed· 35 enrolled
Drug / intervention
Brimonidine +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Circadian Rhythms of Aqueous Humor Dynamics in Subjects With Ocular Hypertension Using Brimonidine
In Brief
A Early Phase 1 clinical trial evaluating Brimonidine and Artificial tears for Intraocular Pressure. Completed, enrolled 35 participants across 1 site.
Detailed Summary
This single-center, investigator-masked, crossover study is designed to investigate the circadian rhythms of aqueous humor dynamics in human subjects with ocular hypertension (OHT) before and after intervention with a commonly used ocular hypotensive medication, brimonidine for six weeks.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsIntraocular Pressure
CountriesUnited States
Collaborators--
Timeline
Early Ph 1CompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
First PostedJun 2010
Enrollment StartAug 2010
Primary CompletionOct 2011
TodayJul 2026
First PostedJun 15, 2010
Enrollment StartAug 1, 2010
Primary CompletionOct 1, 2011
TodayJul 2, 2026
Enrollment to primary: 1.2 yearsPosted 16.0 years ago
Interventions
Brimonidinedrug
One drop of brimonidine in each eye three times a day for six weeks.
Artificial tearsdrug
Lubricating drops added three times a day for six weeks